The active ingredient in OxyContin is oxycodone but OxyContin (a brand name derived from "oxycodone continuous") has a time-release mechanism, which means the drug is released in the body over a period of time and patients have to take the drug less often. Regular oxycodone is an immediate-release drug, an opiod narcotic painkiller used to treat moderate to severe pain.
|Dosage||10mg every 12 hours initially||2.5mg to 10mg orally every 4 to 6 hours, except 12-hour controlled release|
|Form||Time release||Liquid, tablet (both controlled release and immediate release), capsule|
|Use||Relief of moderate to severe pain||Relief of moderate to severe pain|
|Side effects||Include nausea, vomiting, constipation, loss of appetite, dizziness, headache, tiredness, dry mouth, sweating and itching||Nausea, vomiting, constipation, loss of appetite, dizziness, headache, tiredness, dry mouth, sweating and itching|
|Cost||$87.78 per month with insurance||120 tablets of generic Percocet (5mg oxycodone + 325mg acetaminophen) is between $23 and $73.|
|Overdose||Potentially fatal. Same symptoms as oxycodone. Greater risk of overdose||Potentially fatal. Symptoms include extreme drowsiness, muscle weakness, confusion, clammy skin, shallow breathing, fainting and coma|
|Pregnancy||Safe for pregnancy; not safe for breastfeeding||Category B drug in U.S. — may be prescribed if benefit to mother outweighs risk to fetus; not recommended while breastfeeding. Animal reproduction studies have not found adverse effects. Category C drug in Australia.|
Contents: OxyContin vs Oxycodone
Oxycodone is used to treat chronic moderate to severe pain, as well as managing breakthrough or acute excessive pain in patients who are treated for chronic pain. OxyContin has similar pain-killing effects but it's used to treat chronic pain. OxyContin is not effective for immediate pain relief (for example in an emergency room).
The initial adult dose of oxycodone is 5mg to 15mg taken orally every 4 to 6 hours. This can be increased up to 30mg every 4 hours.
Children who weigh over 50kg can take 5mg of oxycodone every 6 hours, which may be raised to 10mg every 3 to 4 hours over time.
OxyContin is only available in time-release form. Its initial dosage is 10mg every 12 hours, increasing to up to 640mg per day in patients with cancer pain. The average daily dose is 105mg per day.
Oxycodone and OxyContin should not be combined with alcohol, as this can lead to death. It should also not be combined with sedatives, tranquilizers, sleeping pills or muscle relaxers.
Controlled-release oxycodone given every 12 hours was comparable with immediate-release oxycodone given four times daily in efficacy and safety, and it provides convenient, twice-daily, around-the-clock treatment for selected patients with persistent back pain that is inadequately controlled by nonopioids or as-needed opioid therapy.
edit Side Effects
Side effects of oxycodone include nausea, vomiting, constipation, loss of appetite, dizziness, headache, tiredness, dry mouth, sweating and itching.
OxyContin has the same side effects.
Everydayhealth reports that oxycodone costs, on average, $18.12 per month for those with insurance. OxyContin costs an average of $87.78 per month with insurance. Oxycodone is a generic active ingredient and there are many manufacturers that sell this drug. On the other hand OxyContin is a brand name drug by Purdue Pharma and like all brand name drugs costs significantly more than generics.
Oxycodone and OxyContin are FDA pregnancy category B and so are not expected to harm an unborn baby. You should not breast feed while taking oxycodone or OxyContin.
Overdose symptoms of oxycodone include extreme drowsiness, muscle weakness, confusion, cold and clammy skin, pinpoint pupils, shallow breathing, slow heart rate, fainting and coma. Overdose can be fatal.
OxyContin has the same overdose symptoms. However, the danger of overdose is more significant in OxyContin than in oxycodone, as there are more milligrams of oxycodone per pill. If OxyContin is chewed, it can release 12 hours worth of medicine in a few minutes.
- Efficacy and safety of controlled-release versus immediate-release oxycodone: randomized, double-blind evaluation in patients with chronic back pain. - NIH.gov
- Oxycodone Information - Drugs.com
- OxyContin Information - Drugs.com
- Oxycodone Side Effects, Dosage, Interactions - EverydayHealth.com
- OxyContin Side Effects, Dosage, Interactions - EverydayHealth.com