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Prozac versus Sertraline comparison chart
Edit this comparison chartProzacSertraline
  • current rating is 2.88/5
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(291 ratings)
  • current rating is 0/5
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Generic Name Fluoxetine
Prescription Required? Yes
Description Anti-Depressant
Storage Conditions Away from Heat, Moisture & Light
Brand Name Prozac, Prozac Weekly, Sarafem
Available as Capsules to be taken with water without being broken open
Classification SSRI
Molecular Weight 345.79
Elimination Half Life Approximately 4-6 days
Storage Temperatures 59° - 86° F (15° - 30° C)
Empirical Formula C17 H18 F3 NO.HCl
Chemical Name (±)-N-methyl-3-phenyl-3- [(a,a,a-trifluoro-p-olyl)oxy] propylamine hydrochloride
Physical Properties White to off-white crystalline solid, with a solubility of 14 mg/mL in water
Administration Route Oral
Introduction (from Wikipedia) Sertraline hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It was introduced to the market by Pfizer in 1991.
Trade names Zoloft, Lustral, Daxid, Deprax, Altruline, Besitran, Eleval, Emergen, Gladem, Implicane, Sedoran, Sealdin, Serivo, Lowfin, Stimuloton, Tresleen, Sertralin Bluefish
AHFS/Drugs.com monograph
MedlinePlus a697048
Pregnancy cat. C
Legal status ℞ Prescription only
Routes Oral
Bioavailability 44%
Protein binding 98.5%
Metabolism Hepatic (N-demethylation mainly by CYP2B6)
Half-life Approximately 26 hours
Excretion Renal
CAS number 79617-96-2
ATC code N06AB06
PubChem CID 68617
DrugBank DB01104
ChemSpider 61881
UNII QUC7NX6WMB
KEGG D02360
ChEBI CHEBI:9123
ChEMBL CHEMBL809
Formula C17H17Cl2N
Mol. mass 306.229 g/mol

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