Prozac versus Sertraline comparison chart
 | Prozac | Sertraline |
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| - current rating is 2.88/5
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- 2
- 3
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- 5
(291 ratings) | - current rating is 0/5
- 1
- 2
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- 5
(0 ratings) |
| Generic Name | Fluoxetine |
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| Prescription Required? | Yes |
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| Description | Anti-Depressant |
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| Storage Conditions | Away from Heat, Moisture & Light |
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| Brand Name | Prozac, Prozac Weekly, Sarafem |
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| Available as | Capsules to be taken with water without being broken open |
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| Classification | SSRI |
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| Molecular Weight | 345.79 |
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| Elimination Half Life | Approximately 4-6 days |
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| Storage Temperatures | 59° - 86° F (15° - 30° C) |
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| Empirical Formula | C17 H18 F3 NO.HCl |
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| Chemical Name | (±)-N-methyl-3-phenyl-3- [(a,a,a-trifluoro-p-olyl)oxy] propylamine hydrochloride |
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| Physical Properties | White to off-white crystalline solid, with a solubility of 14 mg/mL in water |
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| Administration Route | Oral |
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| Introduction (from Wikipedia) | |
Sertraline hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It was introduced to the market by Pfizer in 1991. |
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| Trade names | |
Zoloft, Lustral, Daxid, Deprax, Altruline, Besitran, Eleval, Emergen, Gladem, Implicane, Sedoran, Sealdin, Serivo, Lowfin, Stimuloton, Tresleen, Sertralin Bluefish |
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| AHFS/Drugs.com | |
monograph |
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| MedlinePlus | |
a697048 |
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| Pregnancy cat. | |
C |
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| Legal status | |
℞ Prescription only |
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| Routes | |
Oral |
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| Bioavailability | |
44% |
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| Protein binding | |
98.5% |
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| Metabolism | |
Hepatic (N-demethylation mainly by CYP2B6) |
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| Half-life | |
Approximately 26 hours |
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| Excretion | |
Renal |
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| CAS number | |
79617-96-2 |
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| ATC code | |
N06AB06 |
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| PubChem | |
CID 68617 |
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| DrugBank | |
DB01104 |
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| ChemSpider | |
61881 |
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| UNII | |
QUC7NX6WMB |
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| KEGG | |
D02360 |
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| ChEBI | |
CHEBI:9123 |
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| ChEMBL | |
CHEMBL809 |
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| Formula | |
C17H17Cl2N |
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| Mol. mass | |
306.229 g/mol |
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