Osteoarthritis vs. Rheumatoid Arthritis

Rheumatoid Arthritis

The symptoms and treatment for rheumatoid arthritis (RA) and osteoarthritis are different, and an accurate diagnosis is important for the patient's health. RA is an autoimmune disease where the immune system attacks healthy tissues in the body. Meanwhile, osteoarthritis is caused by aging and regular wear and tear of the body.

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Rheumatoid Arthritis

Presence of symptoms affecting the whole body (systemic) Systemic symptoms are not present. Localized joint pain (Knee and hips) but NO swelling Pain severity is important (mechanical, inflammatory, noctornal, sudden) Dull pain and inflammation Frequent fatigue (afternoon), stiffness, ulnar deviation, muscle atrophy, swelling of the knuckles , synovial Thickness complications: joint fail, depression, Osteoporosis, infections surgical complications
Treatment NSAIDs (short term use) Acetaminophen, Analgesics, exercise NSAIDs, Steroids (Prednisone), DMARDs (Methotrexate), Antimalarial (Plaquenil), Corticosteriods,
Associated symptoms (no systemic symps) fatigue, muscle weakness, fever, organ involvement; Bony enlargement, deformity, instability, restricted movement, joint locked, sleep dist,depression, comorbid conditions (bursitis, fibromyalgia, gout) Frequent feelings of "being sick inside," with fevers, weight loss, or involvement of other organ systems. carpal tunnel Extra-articular manifestations: nodules, vasculitis, pulmonary, cardiac, skin (vasculitis), eye (sjorgen's syndrome, scleritis
Diagnosis x-ray, pain assessment- perarticular and articular source of pain, presence of deformity, evidence of muscle wasting, local inflammation. asymmetrical joints 1- Anemia (ferratin, ion. ion binding capacity) 2- bone (inc ALP) 3- Inflammatory markers (C reactive protein and ESR)
Disease Process Normal wear and tear (chronic degenerative) chronic Autoimmune
Gender Common in both men and women. Before 50 more men than women, after 50 more women than men Affects more women than men
Effusions local inflammation/effusion sometimes Common
Nodules Herberden's & Bouchard's nodes Present, especially on extensor surfaces. Swan neck deformity. Biopsy important to eliminate gouty tophi
Pattern of joints that are affected Asymmetrical & may spread to the other side. Symptoms begin gradually and are often limited to one set of joints, usually the finger joints closest to the fingernails or the thumbs, large weight-bearing joints, Symmetrical - often affects small and large joints on both sides of the body, such as both hands, both wrists or elbows, or the balls of both feet,
Age of onset Over 60 35-45 years old
Severity Less severe More severe
Speed of onset Slow, over years Rapid, within a year
Cause wear and tear associated w/ aging or injury, also caused by injuries to the joints, obesity, heredity, overuse of the joints from sports Classified as an autoimmune disease, No real known cause.-Connection between environmental and genetic factors;female reproductive hormones
Joint symptoms Joints painful but without swelling; affects joints asymmetrically; affects bigger joints such as hips & knees. Localized with variable, progressive course Joints are painful, swollen, and stiff; affects joints symmetrically; affects smaller joints such as hands & ankles. Systemic with exacerbations and remissions
pain w/ movement movement increases pain movement decreases pain
Assessment One or several joints; enlarged, cool, and hard on palpation; Joints are swollen, red, warm, tender, and painful;several joints involved; Extraarticular: Rheumatoid nodules, Sjogrens sydrome, Felty syndrome
Radiologic findings Loss of joint space and articular cartilage, routine wear and tear osteophytes, sclerosis, cysts, loose bodies, alignment Bony erosions, soft tissue swelling, angular deformities,
Lab findings Rheumatoid Factors (RF) negative, transient elevation in ESR related to synovitis RF positive, increased ESR & CRP, antinuclear antibody, arthrocentesis
Genetic Factors Family HX of OA-womenm RA and Leukocyte antigen- female reproductive hormones, Epstein-Barr virus
Interdisciplinary Team collaborate with PT to provide heat or cool packs, positioning, and mobility, Helps control the diseas and decrease intensity and number of exacerbations
Patient Education Keep weight within normal limits, assist with smoking cessation, avoid risk taking activities, avoid/limit participation in recreational sports, wear supportive shoes, do not perform repetitive exercises. Healthy nutrition, report ASE from medication use, teach that RA is systemic and effects many body systems,

Contents: Osteoarthritis vs Rheumatoid Arthritis

edit Cause

Rheumatoid arthritis (RA) is a disease in which your own immune system mistakenly attacks healthy tissue, causing inflammation that damages your joints. No single cause for RA has been found; current theory suggests patients are genetically predisposed to the disease.

On the other hand, Osteoarthritis (OA) is not an autoimmune disease. It is a condition of wear and tear associated with aging or injury. The immune system is not affected. Common causes for OA include joint injury, repetitive strain/use, being overweight as well as genetic predisposition.

edit Signs and symptoms

edit Location of joints involved

With RA, inflammation generally occurs in the knuckles and at the joints closest to your hands, nearer the base of your fingers. On the other hand with OA, inflammation generally occurs at the joint closest to your fingernail.

edit Prevalence

OA is much more common than RA. In the United States alone, an estimated 20 million people have osteoarthritis, and approximately 2.1 million people have RA.

edit References

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Comments: Osteoarthritis vs Rheumatoid Arthritis

Anonymous comments (2)

September 26, 2013, 5:30pm

Don't give up on your search for relief. Try another doctor or get a referral to another rheumatologist. Pray for strength. I pray you find some form of relief. Relaxation techniques, parrafin wax, swimming is a good health maintenance for RA

— 207.✗.✗.226

June 15, 2013, 1:00pm

hurt realyl bad cant use my hands well any more knots on the joints 80 percent over all my family has this RA .. my wrists within the past year have had knots apper on each side swollwen i dont sleep well due to the pain upon awaking i usually have one hour for stiffiness morning mostly or after knapping... to go away . ive been on antidepressants from the depression from losing ability to use limbbs... though my ra test negative """though my esr is extreem elevated."" and i use a diruetic monitered for the swelling in my joints ?. steriods help at times in the swelling. i have a bad vision going blind cause unspecified-""" im only 41 this has happened within the past 18 months..status of loss of vision 20/600 etc a respitory difficulty breathing like not enough entergy to breath . lack of staminia. i am 112 pounds . i lost my appitite almost totally . am current on cymbalta nuro patches pain meds at bad days . spironalactone for swelling. i have nooo entergy what steps can i take when the doctor did one ra rf test but wont investigate more to see what this is.... not normal for a person to go down this drastically in s year. help please email me if you have new information on this condition as i say the doctor did the ra test 18 months ago maybe it wasnt showing up then ... i feel criple i use a cain a walker to get around..

— 184.✗.✗.75


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