Purines vs Pyrimidines

Purines and Pyrimidines are nitrogenous bases that make up the two different kinds of nucleotide bases in DNA and RNA. The two-carbon nitrogen ring bases (adenine and guanine) are purines, while the one-carbon nitrogen ring bases (thymine and cytosine) are pyrimidines.

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Purines

Pyrimidines

Function Production of RNA and DNA, proteins and starches, the regulation of enzymes and cell signaling. Production of RNA and DNA, proteins and starches, the regulation of enzymes and cell signaling.
Nucleobases Adenine and guanine Cytosine, thymine, uracil
Structure A pyrimidine ring fused to a imidazole ring. Contains two carbon-nitrogen rings and four nitrogen atoms. Contains one carbon-nitrogen ring and two nitrogen atoms.
Melting point 214 °C, 487 K, 417 °F 20–22 °C
Type of Compound Heterocyclic aromatic organic compound Heterocyclic aromatic organic compound
Molecular formula C5H4N4 C4H4N2
Molar mass 120.11 g mol−1 80.088 g mol-1
MeSH Purine Pyrimidine
SMILES c1c2c(nc[nH]2)ncn1 C1=CN=CN=C1
Introduction (from Wikipedia) A purine is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. Pyrimidine is a heterocyclic aromatic organic compound similar to benzene and pyridine, containing two nitrogen atoms at positions 1 and 3 of the six-member ring. It is isomeric with two other forms of diazine.
CAS number 120-73-0 289-95-2 Y
PubChem 1044 9260
Synthesis in Lab Traube Purine Synthesis Biginelli Reaction

Contents: Purines vs Pyrimidines

edit Structure

Purine (L) and Pyrimidine (R) molecules, where Black= Carbon, White=Hydrogen, Blue=Nitrogen
Purine (L) and Pyrimidine (R) molecules, where Black= Carbon, White=Hydrogen, Blue=Nitrogen

A purine is a heterocyclic aromatic organic compound containing 4 nitrogen atoms. It contains two carbon rings, and is made of a pyrimidine ring fused to an imidazole ring.

Structure of a purine
Structure of a purine

A pyrimidine is a heterocyclic aromatic organic compound containing 2 nitrogen atoms. It contains only one carbon ring.

Structure of a pyrimidine
Structure of a pyrimidine

edit Function

Both purines and pyrimidines have the same function: they serve as a form of energy for cells, and are essential for production of DNA and RNA, proteins, starch, regulations of enzymes, cell signaling.

edit Nucleobases

Purines make up two of the four nucleobases in DNA and RNA: adenine and guanine.

Pyramidines make up the other bases in DNA and RNA: cytosine, thymine (in DNA) and uracil (in RNA).

edit Synthesis

Purines can be created artificially through Traube purine synthesis.

Pyrimidines can be prepared in a lab using organic synthesis, such as through the Bigineli reaction.

edit References

Comments: Purines vs Pyrimidines

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April 9, 2014, 4:17pm

WHY MITOSIS ARE REPRODUCTIVE CELL AND NOT MEIOSIS

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November 23, 2012, 7:20am

Wanted to get a good understanding of the nucleic acids, I am glad I visited this site.

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